Run for 3.21

Run for 321 National Down Syndrome Society logo. Image of Team NDSS posing for a sunrise on a country road in the Western United States

Run for 3.21 is going to the West Coast! The 2026 Run for 3.21 will take place March 19-21, 2026. The team will run 340+ miles from Los Angeles, CA to Las Vegas, NV beginning at 4am PT on Thursday, March 19 and will finish Saturday March 21, 2026. The team will spend more than 50 hours running relay-style through the Mojave Desert, day and night, to complete the course. Participants must be able to run 35-45 miles over a three-day period in desert-like conditions including uneven terrain, extreme weather, and wildlife.  

The fundraising requirement is $5,000 per runner. Each participant will be responsible for their own transportation to and from the event. A room block will be secured for the night before the event. 

DonateSponsor Run for 3.21 

#TeamNDSS Documentary. Screenshot of a video with two runners wearing bright lights in the dark.

#TeamNDSS Documentary

Check out the Run for 3.21 #TeamNDSS Documentary! Produced by Paragon Productions and Sunspace Films.

Join #TeamNDSS on the West Coast!

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