NDSS Externally Led Patient-Focused Drug Development (EL-PFDD) Meeting. June 2. NDSS logo. Image of an elderly woman sitting in a wheelchair, showing a woman with Down syndrome content on her smart phone.

Share your story with the FDA:

Discuss Down syndrome- associated Alzheimer's disease

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Groups of advocates pose in front of the US Capitol Building

NDSS' mission is to create a world where individuals with Down syndrome thrive.

Honolulu Marathon logo with a graphic of a woman wearing a lei with an orange flower on her head.

Join Team NDSS in Hawai‘i!

NDSS has been chosen as an official charity partner of the Honolulu Marathon for the first time! This race welcomes over 35,000 runners from around the world for a race that includes scenery and the Aloha spirit like nowhere else. Whether you’re a first-timer or returning for another go, you’ll be part of one of the world’s most memorable marathon weekends.

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New York City Buddy Walk logo. National Down Syndrome Society. Educate. Advocate. Celebrate. Image of a man with Down syndrome wearing a Buddy Walk t-shirt and a medal. September 12, 2026.

2026 NYC Buddy Walk®

Since 1995, the National Down Syndrome Society Buddy Walk® has been the premier advocacy event for Down syndrome in the United States. It is also the world’s most widely recognized public awareness program for the Down syndrome community. The flagship New York City Buddy Walk attracts participants from coast to coast each year. Join NDSS on Saturday, September 12, 2026!

Register Today!